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Epstein-Barr Virus-Encoded Latent Membrane Protein 1 and B-Cell Growth Transformation Induce Lipogenesis through Fatty Acid Synthase

Latent membrane protein 1 (LMP1) is the major transforming protein of Epstein-Barr virus (EBV) and is critical for EBV-induced B-cell transformation in vitro. Several B-cell malignancies are associated with latent LMP1-positive EBV infection, including Hodgkin’s and diffuse large B-cell lymphomas. W...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Hulse, Michael, Johnson, Sarah M., Boyle, Sarah, Caruso, Lisa Beatrice, Tempera, Italo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7851568/
https://ncbi.nlm.nih.gov/pubmed/33208446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01857-20
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