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Single-cell RNA-seq dissects the intratumoral heterogeneity of triple-negative breast cancer based on gene regulatory networks

Triple-negative breast cancer (TNBC) is a subtype of breast cancer with high intratumoral heterogeneity. Recent studies revealed that TNBC patients might comprise cells with distinct molecular subtypes. In addition, gene regulatory networks (GRNs) constructed based on single-cell RNA sequencing (scR...

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Publicado en:Mol Ther Nucleic Acids
Autores principales: Zhou, Shunheng, Huang, Yu-e, Liu, Haizhou, Zhou, Xu, Yuan, Mengqin, Hou, Fei, Wang, Lihong, Jiang, Wei
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Gene & Cell Therapy 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7851423/
https://ncbi.nlm.nih.gov/pubmed/33575114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.12.018
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