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Utility of measuring very long-chain fatty-acyl carnitines in dried blood spots for newborn screening of X-linked Adrenoleukodystrophy

We measured C24:0 and C26:0-carnitines in dried blood spots by flow injection analysis-tandem mass spectrometry method to evaluate whether they can be used as markers for newborn screening of X-linked Adrenoleukodystrophy (X-ALD). We found that C26:0-carnitine was 95.1% and 44.7% sensitive for ident...

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Detalhes bibliográficos
Publicado no:Mol Genet Metab Rep
Main Authors: Natarajan, Archana, Christopher, Rita, Palakuzhiyil, Shruti V., Chandra, Sadanandavalli Retnaswami
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7851351/
https://ncbi.nlm.nih.gov/pubmed/33552912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgmr.2021.100720
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