Recombinant CCL17 Enhances Hematoma Resolution and Activation of CCR4/ERK/Nrf2/CD163 Signaling Pathway After Intracerebral Hemorrhage in Mice

Hematoma is a crucial factor leading to poor prognosis after intracerebral hemorrhage (ICH). Promoting microglial phagocytosis to enhance hematoma resolution may be an important therapeutic target for recovery after ICH. C-C chemokine receptor 4 (CCR4) is important for regulating immune balance in t...

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Udgivet i:Neurotherapeutics
Main Authors: Deng, Shuixiang, Sherchan, Prativa, Jin, Peng, Huang, Lei, Travis, Zachary, Zhang, John H., Gong, Ye, Tang, Jiping
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2020
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7851239/
https://ncbi.nlm.nih.gov/pubmed/32783091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-020-00908-4
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