STRN-ALK rearranged pediatric malignant peritoneal mesothelioma – Functional testing of 527 cancer drugs in patient-derived cancer cells

Genetic rearrangements involving the anaplastic lymphoma kinase (ALK) gene create oncogenic drivers for several cancers, including malignant peritoneal mesothelioma (MPeM). Here, we report genomic and functional precision oncology profiling on a rare case of a 5-year old patient diagnosed with wide-...

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Detalhes bibliográficos
Publicado no:Transl Oncol
Main Authors: Murumägi, Astrid, Ungureanu, Daniela, Arjama, Mariliina, Bützow, Ralf, Lohi, Jouko, Sariola, Hannu, Kanerva, Jukka, Koskenvuo, Minna, Kallioniemi, Olli
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2021
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7851186/
https://ncbi.nlm.nih.gov/pubmed/33530027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2021.101027
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