Piglet immunization with a spike subunit vaccine enhances disease by porcine epidemic diarrhea virus

Immunization with an insect cell lysate/baculovirus mixture containing recombinant porcine epidemic diarrhea virus (PEDV) spike protein induced high levels of neutralizing antibodies in both mice and piglets. However, immunization of piglets with this vaccine resulted in enhancement of disease sympt...

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Dettagli Bibliografici
Pubblicato in:NPJ Vaccines
Autori principali: Yu, Jieshi, Sreenivasan, Chithra, Uprety, Tirth, Gao, Rongyuan, Huang, Chen, Lee, Ella J., Lawson, Steven, Nelson, Julie, Christopher-Hennings, Jane, Kaushik, Radhey S., Nelson, Eric, Diel, Diego G., Hause, Ben M., Li, Feng, Wang, Dan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
Soggetti:
Brief Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7851141/
https://ncbi.nlm.nih.gov/pubmed/33526776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-021-00283-x
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