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Notch1 Has an Important Role in β-Cell Mass Determination and Development of Diabetes

BACKGROUND: Notch signaling pathway plays an important role in regulating pancreatic endocrine and exocrine cell fate during pancreas development. Notch signaling is also expressed in adult pancreas. There are few studies on the effect of Notch on adult pancreas. Here, we investigated the role of No...

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Veröffentlicht in:Diabetes Metab J
Hauptverfasser: Eom, Young Sil, Gwon, A-Ryeong, Kwak, Kyung Min, Youn, Jin-Young, Park, Heekyoung, Kim, Kwang-Won, Kim, Byung-Joon
Format: Artigo
Sprache:Inglês
Veröffentlicht: Korean Diabetes Association 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7850870/
https://ncbi.nlm.nih.gov/pubmed/32174059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4093/dmj.2019.0160
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