Targeted next-generation sequencing-based detection of microsatellite instability in colorectal carcinomas

In the present study, we developed a computational method and panel markers to assess microsatellite instability (MSI) using a targeted next-generation sequencing (NGS) platform and compared the performance of our computational method, mSILICO, with that of mSINGS to detect MSI in CRCs. We evaluated...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Lee, Yunbeom, Lee, Ji Ae, Park, Hye Eun, Han, Hyojun, Kim, Yuhnam, Bae, Jeong Mo, Kim, Jung Ho, Cho, Nam-Yun, Kim, Hwang-Phill, Kim, Tae-You, Kang, Gyeong Hoon
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2021
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7850495/
https://ncbi.nlm.nih.gov/pubmed/33524032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0246356
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