Treating Glioblastoma Multiforme (GBM) with super hyperfractionated radiation therapy: Implication of temporal dose fractionation optimization including cancer stem cell dynamics

PURPOSE: A previously developed ordinary differential equation (ODE) that models the dynamic interaction and distinct radiosensitivity between cancer stem cells (CSC) and differentiated cancer cells (DCC) was used to explain the definitive treatment failure in Glioblastoma Multiforme (GBM) for conve...

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Veröffentlicht in:PLoS One
Hauptverfasser: Yu, Victoria Y., Nguyen, Dan, O’Connor, Daniel, Ruan, Dan, Kaprealian, Tania, Chin, Robert, Sheng, Ke
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2021
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7850476/
https://ncbi.nlm.nih.gov/pubmed/33524046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0245676
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