Exploration of novel heterofused 1,2,4-triazine derivative in colorectal cancer

Colorectal cancer (CRC) is the third leading cause of cancer-related deaths in men and in women. The impact of the new pyrazolo[4,3-e]tetrazolo[1,5-b][1,2,4]triazine sulphonamide (MM-129) was evaluated against human colon cancer in vitro and in zebrafish xenografts. Our results show that this new sy...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Hermanowicz, Justyna Magdalena, Szymanowska, Anna, Sieklucka, Beata, Czarnomysy, Robert, Pawlak, Krystyna, Bielawska, Anna, Bielawski, Krzysztof, Kalafut, Joanna, Przybyszewska, Alicja, Surazynski, Arkadiusz, Rivero-Muller, Adolfo, Mojzych, Mariusz, Pawlak, Dariusz
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2021
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7850456/
https://ncbi.nlm.nih.gov/pubmed/33522320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2021.1879803
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