The mutational landscape of spinal chordomas and their sensitive detection using circulating tumor DNA

BACKGROUND: Chordomas are the most common primary spinal column malignancy in the United States. The aim of this study was to determine whether chordomas may be detected by evaluating mutations in circulating tumor DNA (ctDNA). METHODS: Thirty-two patients with a biopsy-confirmed diagnosis of chordo...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Neurooncol Adv
Main Authors: Mattox, Austin K, Yang, Beibei, Douville, Christopher, Lo, Sheng-fu, Sciubba, Daniel, Wolinsky, Jean Paul, Gokaslan, Ziya L, Robison, Jamie, Blair, Cherie, Jiao, Yuchen, Bettegowda, Chetan
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Basic and Translational Investigations
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7850091/
https://ncbi.nlm.nih.gov/pubmed/33543146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdaa173
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