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Mutual inactivation of two RING-finger-type E3 ubiquitin ligases during cell cycle progression
CRL and APC/C belong to the RING-finger-type E3 ligases, and both play important roles in cell cycle regulation. Recently, we found that SAG, a RING component of CRL, acts as an endogenous inhibitor of APC/C by competing with APC2 for E2s binding; while APC/C(CDH1) targets SAG for ubiquitylation and...
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| Veröffentlicht in: | Mol Cell Oncol |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7849741/ https://ncbi.nlm.nih.gov/pubmed/33553599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2020.1837582 |
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