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Biochemical, molecular and clinical aspects of coagulation factor VII and its role in hemostasis and thrombosis

Activated factor VII (FVIIa), the first protease of clotting, expresses its physiological procoagulant potential only after complexing with tissue factor (TF) exposed to blood. Deep knowledge of the FVIIa-TF complex and F7 gene helps to understand the Janus-faced clinical findings associated to low...

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Détails bibliographiques
Publié dans:Haematologica
Auteurs principaux: Bernardi, Francesco, Mariani, Guglielmo
Format: Artigo
Langue:Inglês
Publié: Fondazione Ferrata Storti 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849579/
https://ncbi.nlm.nih.gov/pubmed/33406812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2020.248542
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