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Biochemical, molecular and clinical aspects of coagulation factor VII and its role in hemostasis and thrombosis

Activated factor VII (FVIIa), the first protease of clotting, expresses its physiological procoagulant potential only after complexing with tissue factor (TF) exposed to blood. Deep knowledge of the FVIIa-TF complex and F7 gene helps to understand the Janus-faced clinical findings associated to low...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Haematologica
Hauptverfasser: Bernardi, Francesco, Mariani, Guglielmo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Fondazione Ferrata Storti 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849579/
https://ncbi.nlm.nih.gov/pubmed/33406812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2020.248542
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