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Biochemical, molecular and clinical aspects of coagulation factor VII and its role in hemostasis and thrombosis

Activated factor VII (FVIIa), the first protease of clotting, expresses its physiological procoagulant potential only after complexing with tissue factor (TF) exposed to blood. Deep knowledge of the FVIIa-TF complex and F7 gene helps to understand the Janus-faced clinical findings associated to low...

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Detalhes bibliográficos
Publicado no:Haematologica
Main Authors: Bernardi, Francesco, Mariani, Guglielmo
Formato: Artigo
Idioma:Inglês
Publicado em: Fondazione Ferrata Storti 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849579/
https://ncbi.nlm.nih.gov/pubmed/33406812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2020.248542
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