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Elimination of macrophages reduces glutaraldehyde‐fixed porcine heart valve degeneration in mice subdermal model

Glutaraldehyde‐fixed porcine heart valve (GPHV) calcify and deteriorate over time. The aim of this study was to explore the roles macrophages play in mediating calcification and degeneration of the valve's connective tissue matrix. GPHV were implanted subcutaneously in the abdomens of C57BL/6 m...

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Detalhes bibliográficos
Publicado no:Pharmacol Res Perspect
Main Authors: Liu, Zongtao, Wang, Yixuan, Xie, Fei, Liu, Xing, Li, Fei, Dong, Nianguo
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849454/
https://ncbi.nlm.nih.gov/pubmed/33523576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.716
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