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Effects of transcriptional noise on estimates of gene and transcript expression in RNA sequencing experiments

RNA sequencing is widely used to measure gene expression across a vast range of animal and plant tissues and conditions. Most studies of computational methods for gene expression analysis use simulated data to evaluate the accuracy of these methods. These simulations typically include reads generate...

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Veröffentlicht in:Genome Res
Hauptverfasser: Varabyou, Ales, Salzberg, Steven L., Pertea, Mihaela
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849408/
https://ncbi.nlm.nih.gov/pubmed/33361112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.266213.120
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