Lamin B1 decline underlies age‐related loss of adult hippocampal neurogenesis

Neurogenesis in the adult hippocampus declines with age, a process that has been implicated in cognitive and emotional impairments. However, the mechanisms underlying this decline have remained elusive. Here, we show that the age‐dependent downregulation of lamin B1, one of the nuclear lamins in adu...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Bedrosian, Tracy A, Houtman, Judith, Eguiguren, Juan Sebastian, Ghassemzadeh, Saeed, Rund, Nicole, Novaresi, Nicole M, Hu, Lauren, Parylak, Sarah L., Denli, Ahmet M, Randolph‐Moore, Lynne, Namba, Takashi, Gage, Fred H, Toda, Tomohisa
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849303/
https://ncbi.nlm.nih.gov/pubmed/33300615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020105819
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