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1,2,3-Triazoles as leaving groups in S(N)Ar–Arbuzov reactions: synthesis of C6-phosphonated purine derivatives

A new method for C–N bond transformations into C–P bonds was developed using 1,2,3-triazoles as leaving groups in S(N)Ar–Arbuzov reactions. A series of C6-phosphonated 2-triazolylpurine derivatives was synthesized for the first time, with the isolated yields reaching up to 82% in the C–P-bond-formin...

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Kriķis, Kārlis-Ēriks, Novosjolova, Irina, Mishnev, Anatoly, Turks, Māris
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849246/
https://ncbi.nlm.nih.gov/pubmed/33564329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.17.19
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