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Modulation of Yorkie activity by alternative splicing is required for developmental stability

The Hippo signaling pathway is a major regulator of organ growth, which controls the activity of the transcription coactivator Yorkie (Yki) in Drosophila and its homolog YAP in mammals. Both Yki and YAP proteins exist as alternatively spliced isoforms containing either one or two WW domains. The bio...

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Bibliografische gegevens
Gepubliceerd in:EMBO J
Hoofdauteurs: Srivastava, Diwas, de Toledo, Marion, Manchon, Laurent, Tazi, Jamal, Juge, François
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849169/
https://ncbi.nlm.nih.gov/pubmed/33320356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020104895
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