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Apoptosis Induced by (+)-Betulin Through NF-κB Inhibition in MDA-MB-231 Breast Cancer Cells

BACKGROUND/AIM: This study aims to uncover the effects of (+)-betulin on the NF-κB-apoptotic pathway in MDA-MB-231 cells, and to determine toxicity and protein expression in vivo. MATERIALS AND METHODS: Cell cytotoxicity and toxicity were determined using the SRB assay and a zebrafish model, respect...

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Détails bibliographiques
Publié dans:Anticancer Res
Auteurs principaux: Anaya-Eugenio, Gerardo D., Eggers, Nicole A., Ren, Yulin, Rivera-Chávez, José, Kinghorn, A. Douglas, de Blanco, Esperanza J. Carcache
Format: Artigo
Langue:Inglês
Publié: 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849021/
https://ncbi.nlm.nih.gov/pubmed/33288558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/anticanres.14688
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