Burkholderia pseudomallei Clinical Isolates Are Highly Susceptible In Vitro to Cefiderocol, a Siderophore Cephalosporin

Cefiderocol is a cephalosporin designed to treat multidrug-resistant Gram-negative infections. By forming a chelated complex with ferric iron, cefiderocol is transported into the periplasmic space via bacterial iron transport systems and primarily binds to penicillin-binding protein 3 (PBP3) to inhi...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Burnard, Delaney, Robertson, Gemma, Henderson, Andrew, Falconer, Caitlin, Bauer, Michelle J., Cottrell, Kyra, Gassiep, Ian, Norton, Robert, Paterson, David L., Harris, Patrick N. A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Susceptibility
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7848980/
https://ncbi.nlm.nih.gov/pubmed/33168603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00685-20
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