Growth hormone-releasing hormone agonists ameliorate chronic kidney disease-induced heart failure with preserved ejection fraction

Therapies for heart failure with preserved ejection fraction (HFpEF) are lacking. Growth hormone-releasing hormone agonists (GHRH-As) have salutary effects in ischemic and nonischemic heart failure animal models. Accordingly, we hypothesized that GHRH-A treatment ameliorates chronic kidney disease (...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Rieger, Angela C., Bagno, Luiza L., Salerno, Alessandro, Florea, Victoria, Rodriguez, Jose, Rosado, Marcos, Turner, Darren, Dulce, Raul A., Takeuchi, Lauro M., Kanashiro-Takeuchi, Rosemeire M., Buchwald, Peter, Wanschel, Amarylis C. B. A., Balkan, Wayne, Schulman, Ivonne H., Schally, Andrew V., Hare, Joshua M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7848727/
https://ncbi.nlm.nih.gov/pubmed/33468654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2019835118
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