CRISPR-Cas13-Mediated Knockdown of lncRNA-GACAT3 Inhibited Cell Proliferation and Motility, and Induced Apoptosis by Increasing p21, Bax, and E-Cadherin Expression in Bladder Cancer

The current study is to investigate the expression pattern and biological function of long non-coding RNA Focally gastric cancer-associated transcript3 (GACAT3) in bladder cancer. Real-time quantitative qPCR was used to detect the expression level of GACAT-3 in tumor tissues and paired normal tissue...

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Vydáno v:Front Mol Biosci
Hlavní autoři: Zhang, Zhongfu, Chen, Jieqing, Zhu, Zhongshuang, Zhu, Zhongqing, Liao, Xinhui, Wu, Jianting, Cheng, Jianli, Zhang, Xintao, Mei, Hongbing, Yang, Guosheng
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Molecular Biosciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7848205/
https://ncbi.nlm.nih.gov/pubmed/33537343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2020.627774
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