Patient‐derived organoids of bladder cancer recapitulate antigen expression profiles and serve as a personal evaluation model for CAR‐T cells in vitro

OBJECTIVES: Recent advances in patient‐derived cancer organoids have opened a new avenue for personalised medicine. We aimed to establish an in vitro technological platform to evaluate chimeric antigen receptor (CAR)‐T cell‐mediated cytotoxicity against bladder cancer. METHODS: Patient‐derived bladd...

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Detalhes bibliográficos
Publicado no:Clin Transl Immunology
Main Authors: Yu, Lei, Li, Zhichao, Mei, Hongbin, Li, Wujiao, Chen, Dong, Liu, Lisa, Zhang, Zhongfu, Sun, Yangyang, Song, Fei, Chen, Wei, Huang, Weiren
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7847802/
https://ncbi.nlm.nih.gov/pubmed/33552510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cti2.1248
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