Overall survival of pancreatic ductal adenocarcinoma is doubled by Aldh7a1 deletion in the KPC mouse

Rationale: The activity of aldehyde dehydrogenase 7A1 (ALDH7A1), an enzyme that catalyzes the lipid peroxidation of fatty aldehydes was found to be upregulated in pancreatic ductal adenocarcinoma (PDAC). ALDH7A1 knockdown significantly reduced tumor formation in PDAC. We raised a question how ALDH7A...

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Bibliografiske detaljer
Udgivet i:Theranostics
Main Authors: Lee, Jae-Seon, Lee, Ho, Woo, Sang Myung, Jang, Hyonchol, Jeon, Yoon, Kim, Hee Yeon, Song, Jaewhan, Lee, Woo Jin, Hong, Eun Kyung, Park, Sang-Jae, Han, Sung-Sik, Kim, Soo-Youl
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2021
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7847681/
https://ncbi.nlm.nih.gov/pubmed/33537098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.53935
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