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The effect of fingolimod on regulatory T cells in a mouse model of brain ischaemia

BACKGROUND: The role of the immune system in stroke is well-recognised. Fingolimod, an immunomodulatory agent licensed for the management of relapsing-remitting multiple sclerosis, has been shown to provide benefit in rodent models of stroke. Its mechanism of action, however, remains unclear. We hyp...

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Détails bibliographiques
Publié dans:J Neuroinflammation
Auteurs principaux: Malone, Kyle, Diaz Diaz, Andrea C., Shearer, Jennifer A., Moore, Anne C., Waeber, Christian
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2021
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7847573/
https://ncbi.nlm.nih.gov/pubmed/33516262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-021-02083-5
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