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Self-organizing maps with variable neighborhoods facilitate learning of chromatin accessibility signal shapes associated with regulatory elements

BACKGROUND: Assigning chromatin states genome-wide (e.g. promoters, enhancers, etc.) is commonly performed to improve functional interpretation of these states. However, computational methods to assign chromatin state suffer from the following drawbacks: they typically require data from multiple ass...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:BMC Bioinformatics
Egile Nagusiak: Eicher, Tara, Chan, Jany, Luu, Han, Machiraju, Raghu, Mathé, Ewy A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7847148/
https://ncbi.nlm.nih.gov/pubmed/33516170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-021-03976-1
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