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ACE2/Ang-(1-7)/Mas1 axis and the vascular system: vasoprotection to COVID-19-associated vascular disease

The two axes of the renin–angiotensin system include the classical ACE/Ang II/AT1 axis and the counter-regulatory ACE2/Ang-(1-7)/Mas1 axis. ACE2 is a multifunctional monocarboxypeptidase responsible for generating Ang-(1-7) from Ang II. ACE2 is important in the vascular system where it is found in a...

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Détails bibliographiques
Publié dans:Clin Sci (Lond)
Auteurs principaux: Kuriakose, Jithin, Montezano, Augusto C., Touyz, Rhian M.
Format: Artigo
Langue:Inglês
Publié: Portland Press Ltd. 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7846970/
https://ncbi.nlm.nih.gov/pubmed/33511992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20200480
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