Downregulation of Retinal Connexin 43 in GFAP-Expressing Cells Modifies Vasoreactivity Induced by Perfusion Ocular Pressure Changes

PURPOSE: Glia and their communication via connexin 43 (Cx43) gap junctions are known to mediate neurovascular coupling, a process driven by metabolic demand. However, it is unclear whether Cx43 mediated glial communication intermediates classical autoregulation. Here we used viral transfection and a...

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Bibliografiske detaljer
Udgivet i:Invest Ophthalmol Vis Sci
Main Authors: Liu, Guodong, Li, Hui, Cull, Grant, Wilsey, Laura, Yang, Hongli, Reemmer, Jesica, Shen, Hai-Ying, Wang, Fang, Fortune, Brad, Bui, Bang V., Wang, Lin
Format: Artigo
Sprog:Inglês
Udgivet: The Association for Research in Vision and Ophthalmology 2021
Fag:
Physiology and Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7846954/
https://ncbi.nlm.nih.gov/pubmed/33502459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.62.1.26
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