Burkholderia pseudomallei OMVs derived from infection mimicking conditions elicit similar protection to a live-attenuated vaccine

Burkholderia pseudomallei is a Gram-negative, facultative intracellular bacillus that causes the disease melioidosis. B. pseudomallei expresses a number of proteins that contribute to its intracellular survival in the mammalian host. We previously demonstrated that immunization with OMVs derived fro...

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Vydáno v:NPJ Vaccines
Hlavní autoři: Baker, Sarah M., Settles, Erik W., Davitt, Christopher, Gellings, Patrick, Kikendall, Nicole, Hoffmann, Joseph, Wang, Yihui, Bitoun, Jacob, Lodrigue, Kasi-Russell, Sahl, Jason W., Keim, Paul, Roy, Chad, McLachlan, James, Morici, Lisa A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7846723/
https://ncbi.nlm.nih.gov/pubmed/33514749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-021-00281-z
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