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Polymerization in the Actin ATPase clan regulates hexokinase activity in yeast

The actin fold is found in cytoskeletal polymers, chaperones, and various metabolic enzymes. Many actin-fold proteins, like the carbohydrate kinases, do not polymerize. We found that Glk1, a Saccharomyces cerevisiae glucokinase, forms two-stranded filaments with unique ultrastructure, distinct from...

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Publicat a:Science
Autors principals: Stoddard, Patrick R, Lynch, Eric M., Farrell, Daniel P., Dosey, Annie M., DiMaio, Frank, Williams, Tom A., Kollman, Justin M., Murray, Andrew W., Garner, Ethan C.
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7846450/
https://ncbi.nlm.nih.gov/pubmed/32108112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aay5359
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