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Promoter Activity-Based Case-Control Association Study on SLC6A4 Highlighting Hypermethylation and Altered Amygdala Volume in Male Patients With Schizophrenia

Associations between altered DNA methylation of the serotonin transporter (5-HTT)-encoding gene SLC6A4 and early life adversity, mood and anxiety disorders, and amygdala reactivity have been reported. However, few studies have examined epigenetic alterations of SLC6A4 in schizophrenia (SZ). We exami...

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Publié dans:Schizophr Bull
Auteurs principaux: Ikegame, Tempei, Bundo, Miki, Okada, Naohiro, Murata, Yui, Koike, Shinsuke, Sugawara, Hiroko, Saito, Takeo, Ikeda, Masashi, Owada, Keiho, Fukunaga, Masaki, Yamashita, Fumio, Koshiyama, Daisuke, Natsubori, Tatsunobu, Iwashiro, Norichika, Asai, Tatsuro, Yoshikawa, Akane, Nishimura, Fumichika, Kawamura, Yoshiya, Ishigooka, Jun, Kakiuchi, Chihiro, Sasaki, Tsukasa, Abe, Osamu, Hashimoto, Ryota, Iwata, Nakao, Yamasue, Hidenori, Kato, Tadafumi, Kasai, Kiyoto, Iwamoto, Kazuya
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7846196/
https://ncbi.nlm.nih.gov/pubmed/32556264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbaa075
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