A novel sialic acid-binding adhesin present in multiple species contributes to the pathogenesis of Infective endocarditis

Bacterial binding to platelets is a key step in the development of infective endocarditis (IE). Sialic acid, a common terminal carbohydrate on host glycans, is the major receptor for streptococci on platelets. So far, all defined interactions between streptococci and sialic acid on platelets are med...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Gaytán, Meztlli O., Singh, Anirudh K., Woodiga, Shireen A., Patel, Surina A., An, Seon-Sook, Vera-Ponce de León, Arturo, McGrath, Sean, Miller, Anthony R., Bush, Jocelyn M., van der Linden, Mark, Magrini, Vincent, Wilson, Richard K., Kitten, Todd, King, Samantha J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7846122/
https://ncbi.nlm.nih.gov/pubmed/33465168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009222
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