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Bacterial fitness landscapes stratify based on proteome allocation associated with discrete aero-types

The fitness landscape is a concept commonly used to describe evolution towards optimal phenotypes. It can be reduced to mechanistic detail using genome-scale models (GEMs) from systems biology. We use recently developed GEMs of Metabolism and protein Expression (ME-models) to study the distribution...

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Библиографические подробности
Опубликовано в: :PLoS Comput Biol
Главные авторы: Chen, Ke, Anand, Amitesh, Olson, Connor, Sandberg, Troy E., Gao, Ye, Mih, Nathan, Palsson, Bernhard O.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7846111/
https://ncbi.nlm.nih.gov/pubmed/33465077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008596
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