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In vitro mutagenicity of selected environmental carcinogens and their metabolites in MutaMouse FE1 lung epithelial cells

Chemicals in commerce or under development must be assessed for genotoxicity; assessment is generally conducted using validated assays (e.g. Tk mouse lymphoma assay) as part of a regulatory process. Currently, the MutaMouse FE1 cell mutagenicity assay is undergoing validation for eventual use as a s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mutagenesis
Hauptverfasser: Hölzl-Armstrong, Lisa, Nævisdal, Andrea, Cox, Julie A, Long, Alexandra S, Chepelev, Nikolai L, Phillips, David H, White, Paul A, Arlt, Volker M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7846080/
https://ncbi.nlm.nih.gov/pubmed/33399867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/mutage/geaa032
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