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Small molecule-RNA targeting: Starting with the fundamentals

The structural and regulatory elements in therapeutically relevant RNAs offer many opportunities for targeting by small molecules, yet fundamental understanding of what drives selectivity in small molecule:RNA recognition has been a recurrent challenge. In particular, RNAs tend to be more dynamic an...

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Publicat a:Chem Commun (Camb)
Autor principal: Hargrove, Amanda E.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7845941/
https://ncbi.nlm.nih.gov/pubmed/33201954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0cc06796b
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