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High-fidelity reconstitution of stress granules and nucleoli in mammalian cellular lysate

Liquid–liquid phase separation (LLPS) is a mechanism of intracellular organization that underlies the assembly of a variety of RNP granules. Fundamental biophysical principles governing LLPS during granule assembly have been revealed by simple in vitro systems, but these systems have limitations whe...

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Bibliographische Detailangaben
Veröffentlicht in:J Cell Biol
Hauptverfasser: Freibaum, Brian D., Messing, James, Yang, Peiguo, Kim, Hong Joo, Taylor, J. Paul
Format: Artigo
Sprache:Inglês
Veröffentlicht: Rockefeller University Press 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7845923/
https://ncbi.nlm.nih.gov/pubmed/33502444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202009079
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