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Atypical Divergence of SARS-CoV-2 Orf8 from Orf7a within the Coronavirus Lineage Suggests Potential Stealthy Viral Strategies in Immune Evasion

Orf8, one of the most puzzling genes in the SARS lineage of coronaviruses, marks a unique and striking difference in genome organization between SARS-CoV-2 and SARS-CoV-1. Here, using sequence comparisons, we unequivocally reveal the distant sequence similarities between SARS-CoV-2 Orf8 with its SAR...

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Bibliografiska uppgifter
I publikationen:mBio
Huvudupphovsmän: Neches, Russell Y., Kyrpides, Nikos C., Ouzounis, Christos A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7845636/
https://ncbi.nlm.nih.gov/pubmed/33468697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.03014-20
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