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Inhibition of Carbonic Anhydrase IX by Ureidosulfonamide Inhibitor U104 Reduces Prostate Cancer Cell Growth, But Does Not Modulate Daunorubicin or Cisplatin Cytotoxicity

Carbonic anhydrase (CA) IX has emerged as a promising target for cancer therapy. It is highly upregulated in hypoxic regions and mediates pH regulation critical for tumor cell survival as well as extracellular acidification of the tumor microenvironment, which promotes tumor aggressiveness via vario...

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Bibliografski detalji
Izdano u:Oncol Res
Glavni autori: Riemann, Anne, Güttler, Antje, Haupt, Verena, Wichmann, Henri, Reime, Sarah, Bache, Matthias, Vordermark, Dirk, Thews, Oliver
Format: Artigo
Jezik:Inglês
Izdano: Cognizant Communication Corporation 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7844713/
https://ncbi.nlm.nih.gov/pubmed/28631600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/096504017X14965111926391
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