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Dexmedetomidine Inhibits Osteosarcoma Cell Proliferation and Migration, and Promotes Apoptosis by Regulating miR-520a-3p

This study aimed to investigate the effect of dexmedetomidine (DEX) on osteosarcoma (OS) cell line MG63 and to explore the possible relationship between DEX and miR-520-3p in OS. The results showed that DEX could upregulate miR-520-3p, which directly targeted AKT1. Additionally, miR-520-3p also inhi...

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Détails bibliographiques
Publié dans:Oncol Res
Auteurs principaux: Wang, Xiaoyan, Xu, Yongguang, Chen, Xinlei, Xiao, Jianmin
Format: Artigo
Langue:Inglês
Publié: Cognizant Communication Corporation 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7844699/
https://ncbi.nlm.nih.gov/pubmed/28653601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/096504017X14982578608217
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