VNTR2/VNTR3 genotype in the FCGRT gene is associated with reduced effectiveness of intravenous immunoglobulin in patients with myasthenia gravis

BACKGROUND: Intravenous immunoglobulin (IVIG) has been commonly used to treat myasthenia gravis exacerbation, but is still ineffective in nearly 30% of patients. A variable number of tandem repeat (VNTR) polymorphism in the FCGRT gene has been found to reduce the efficiency of IgG biologics. However...

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Gepubliceerd in:Ther Adv Neurol Disord
Hoofdauteurs: Su, Shengyao, Liu, Qing, Zhang, Xueping, Wen, Xinmei, Lei, Lin, Shen, Faxiu, Fan, Zhirong, Duo, Jianying, Lu, Yan, Di, Li, Wang, Min, Chen, Hai, Zhu, Wenjia, Xu, Min, Wang, Suobin, Da, Yuwei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: SAGE Publications 2021
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Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7844454/
https://ncbi.nlm.nih.gov/pubmed/33552238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756286420986747
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