Hyperpolyploidization of hepatocyte initiates preneoplastic lesion formation in the liver

Hepatocellular carcinoma (HCC) is the most predominant primary malignancy in the liver. Genotoxic and genetic models have revealed that HCC cells are derived from hepatocytes, but where the critical region for tumor foci emergence is and how this transformation occurs are still unclear. Here, hyperp...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Nat Commun
मुख्य लेखकों: Lin, Heng, Huang, Yen-Sung, Fustin, Jean-Michel, Doi, Masao, Chen, Huatao, Lai, Hui-Huang, Lin, Shu-Hui, Lee, Yen-Lurk, King, Pei-Chih, Hou, Hsien-San, Chen, Hao-Wen, Young, Pei-Yun, Chao, Hsu-Wen
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group UK 2021
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7844417/
https://ncbi.nlm.nih.gov/pubmed/33510150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20572-8
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