In-depth quantitative proteomic characterization of organotypic hippocampal slice culture reveals sex-specific differences in biochemical pathways

Sex differences in the brain of mammals range from neuroarchitecture through cognition to cellular metabolism. The hippocampus, a structure mostly associated with learning and memory, presents high vulnerability to neurodegeneration and aging. Therefore, we explored basal sex-related differences in...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Weis, Simone Nardin, Souza, Jaques Miranda F., Hoppe, Juliana Bender, Firmino, Marina, Auer, Manfred, Ataii, Nassim N., da Silva, Leonardo Assis, Gaelzer, Mariana Maier, Klein, Caroline Peres, Mól, Alan R., de Lima, Consuelo M. R., Souza, Diogo Onofre, Salbego, Christianne G., Ricart, Carlos André O., Fontes, Wagner, de Sousa, Marcelo Valle
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7844295/
https://ncbi.nlm.nih.gov/pubmed/33510253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-82016-7
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