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Long non-coding RNA Meg3 deficiency impairs glucose homeostasis and insulin signaling by inducing cellular senescence of hepatic endothelium in obesity

Obesity-induced insulin resistance is a risk factor for diabetes and cardiovascular disease. However, the mechanisms underlying endothelial senescence in obesity, and how it impacts obesity-induced insulin resistance remain incompletely understood. In this study, transcriptome analysis revealed that...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Cheng, Xiao, Shihabudeen Haider Ali, Mohamed Sham, Moran, Matthew, Viana, Martonio Ponte, Schlichte, Sarah L., Zimmerman, Matthew C., Khalimonchuk, Oleh, Feinberg, Mark W., Sun, Xinghui
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7844131/
https://ncbi.nlm.nih.gov/pubmed/33508742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2021.101863
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