SNPs in the 3′-untranslated region of SLC30A8 confer risk of type 2 diabetes mellitus in a south-east Iranian population: Evidences from case-control and bioinformatics studies

BACKGROUND: Type 2 diabetes mellitus (T2DM) is a heterogenic disease with increasing incidence. The SLC30A8 gene encodes an islet zinc transporter (ZnT8), and its variants have been associated with glucose and pro-insulin levels. This study was aimed to examine the effects of a missense variant (rs1...

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Vydáno v:J Diabetes Metab Disord
Hlavní autoři: Sargazi, Saman, Heidari Nia, Milad, Sargazi, Fariba Mirani, Sheervalilou, Roghayeh, Saravani, Ramin, Mirinejad, Shekoufeh
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7843856/
https://ncbi.nlm.nih.gov/pubmed/33553018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40200-020-00590-5
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