Human amnion-derived mesenchymal stem cells attenuate xenogeneic graft-versus-host disease by preventing T cell activation and proliferation

Acute graft-versus-host disease (GVHD) is characterized by severe tissue damage that is a life-threatening complication of allogeneic hematopoietic stem cell transplantation. Due to their immunosuppressive properties, mesenchymal stem cells (MSC) have been increasingly examined for the treatment of...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Tago, Yoshiyuki, Kobayashi, Chiho, Ogura, Mineko, Wada, Jutaro, Yamaguchi, Sho, Yamaguchi, Takashi, Hayashi, Masahiro, Nakaishi, Tomoyuki, Kubo, Hiroshi, Ueda, Yasuyoshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7843654/
https://ncbi.nlm.nih.gov/pubmed/33510297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-81916-y
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