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Hypoxic stress increases NF-κB and iNOS mRNA expression in normal, but not in keratoconus corneal fibroblasts

BACKGROUND: Keratoconus (KC) is associated with oxidative stress and hypoxia and as several times discussed, potentially with inflammatory components. Inflammation, hypoxia, and oxidative stress may result in metabolic dysfunction and are directly linked to each other. In the current study, we inves...

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Détails bibliographiques
Publié dans:Graefes Arch Clin Exp Ophthalmol
Auteurs principaux: Stachon, Tanja, Latta, Lorenz, Seitz, Berthold, Szentmáry, Nóra
Format: Artigo
Langue:Inglês
Publié: Springer Berlin Heidelberg 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7843574/
https://ncbi.nlm.nih.gov/pubmed/32886165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00417-020-04900-8
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