Hepatic synthesis of triacylglycerols containing medium-chain fatty acids is dominated by diacylglycerol acyltransferase 1 and efficiently inhibited by etomoxir

OBJECTIVE: Medium-chain fatty acids (MCFAs) play an increasing role in human nutrition. In the liver, one fraction is used for synthesis of MCFA-containing triacylglycerol (MCFA-TG), and the rest is used for oxidative energy production or ketogenesis. We investigated which enzymes catalyse the synth...

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Gepubliceerd in:Mol Metab
Hoofdauteurs: Wunderling, Klaus, Leopold, Christina, Jamitzky, Isabell, Yaghmour, Mohamed, Zink, Fabian, Kratky, Dagmar, Thiele, Christoph
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2020
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7843514/
https://ncbi.nlm.nih.gov/pubmed/33359403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2020.101150
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