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Basolateral activation with TLR agonists induces polarized cytokine release and reduces barrier function in RPE in vitro
PURPOSE: Systemic inflammation may be of importance in the development of AMD. RPE cells can recognize danger signals with toll-like receptors (TLR) and may react in a pro-inflammatory manner. In this study, we evaluated the basal and apical secretions of TNFα, IL-6, and IL-1β in primary RPE cells a...
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| Publicado no: | Graefes Arch Clin Exp Ophthalmol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7843481/ https://ncbi.nlm.nih.gov/pubmed/32949301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00417-020-04930-2 |
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