The integrated stress response mediates necrosis in murine Mycobacterium tuberculosis granulomas

The mechanism by which only some individuals infected with Mycobacterium tuberculosis develop necrotic granulomas with progressive disease while others form controlled granulomas that contain the infection remains poorly defined. Mice carrying the sst1-suscepible (sst1(S)) genotype develop necrotic...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Bhattacharya, Bidisha, Xiao, Shiqi, Chatterjee, Sujoy, Urbanowski, Michael, Ordonez, Alvaro, Ihms, Elizabeth A., Agrahari, Garima, Lun, Shichun, Berland, Robert, Pichugin, Alexander, Gao, Yuanwei, Connor, John, Ivanov, Alexander R., Yan, Bo-Shiun, Kobzik, Lester, Koo, Bang-Bon, Jain, Sanjay, Bishai, William, Kramnik, Igor
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7843230/
https://ncbi.nlm.nih.gov/pubmed/33301427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI130319
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