Systemic Overexpression of GDF5 in Adipocytes but Not Hepatocytes Alleviates High-Fat Diet-Induced Nonalcoholic Fatty Liver in Mice

OBJECTIVE: Our recent study demonstrated that growth differentiation factor 5 (GDF5) could promote white adipose tissue thermogenesis and alleviate high-fat diet- (HFD-) induced obesity in fatty acid-binding protein 4- (Fabp4-) GDF5 transgenic mice (TG). Here, we further investigated the effects of...

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Vydáno v:Can J Gastroenterol Hepatol
Hlavní autoři: Yang, Yan, Zhang, Wenting, Wu, Xiaohui, Wu, Jing, Sun, Chengjun, Luo, Feihong, Pei, Zhou
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2021
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7843185/
https://ncbi.nlm.nih.gov/pubmed/33542911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/8894685
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